Australian golfer James Nitties is poised to reclaim a US PGA Tour card after storming to a runaway victory on the Nationwide Tour.

Nitties fired a closing six-under-par 65 with seven birdies to win the Midwest Classic in Overland Park, Kansas by five strokes at 26-under 258.

Fellow Newcastle, NSW product Nick Flanagan tied second with Sweden's Jonas Blixt after a 68 and would have had second place money on his own but for a bogey on the last.

Nitties is playing the secondary tour after losing his main tour card last season but appears set for a swift return as his $US99,000 first prize money lifted him from 63rd to 12th on the money list.

The top 25 at the end of the season get US PGA Tour Cards.

It's been four years since Flanagan won three times in a season on the Nationwide Tour to earn instant promotion to the main tour.

He only lasted one year there before dropping back.

And he still has plenty of work to do after climbing from 138th to 63rd on the money list with his $US,40,400 share of second place on Sunday.